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Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells

BACKGROUND-: Specific types of high risk Human papillomaviruses (HR-HPVs) particularly, HPV types 16 and 18 cause cervical cancer and while the two recently developed vaccines against these HPV types are prophylactic in nature, therapeutic options for treatment and management of already existing HPV...

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Autores principales: Mahata, Sutapa, Bharti, Alok C, Shukla, Shirish, Tyagi, Abhishek, Husain, Syed A, Das, Bhudev C
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098825/
https://ncbi.nlm.nih.gov/pubmed/21496227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-39
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