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Molecular epidemiology of Plasmodium vivax anti-folate resistance in India

BACKGROUND: Sulphadoxine and pyrimethamine are anti-folate drugs that show synergistic anti-malarial effect. Point mutations in dihydrofolate reductase (dhfr) and dihydropteorate synthatase (dhps) cause anti-folate drug resistance phenotype in human malaria parasites. This study presents pattern of...

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Detalhes bibliográficos
Main Authors: Prajapati, Surendra K, Joshi, Hema, Dev, Vas, Dua, Virendra K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098820/
https://ncbi.nlm.nih.gov/pubmed/21513569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-102
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