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Sequential interim analyses of survival data in DNA microarray experiments

BACKGROUND: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Frequently, microarray studies are performed to identify genes of which the expression levels in pretherapeutic tissue sample...

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Detalhes bibliográficos
Main Authors: Leha, Andreas, Beißbarth, Tim, Jung, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098786/
https://ncbi.nlm.nih.gov/pubmed/21527044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-127
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