Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues,

Methyl-coenzyme M reductase (MCR) catalyzes the final and rate-limiting step in methane biogenesis; the reduction of methyl-coenzyme M (methyl-SCoM) by coenzyme B (CoBSH) to methane and a heterodisulfide (CoBS-SCoM). Crystallographic studies show that the active site is deeply buried within the enzy...

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Hlavní autoři: Cedervall, Peder E., Dey, Mishtu, Pearson, Arwen R., Ragsdale, Stephen W., Wilmot, Carrie M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098740/
https://ncbi.nlm.nih.gov/pubmed/20707311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100458d
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