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Muscle-specific expression of insulin-like growth factor 1 improves outcome in Lama2(Dy-w) mice, a model for congenital muscular dystrophy type 1A

MDC1A, the second most prevalent form of congenital muscular dystrophy, results from laminin-α2 chain deficiency. This disease is characterized by extensive muscle wasting that results in extremely weak skeletal muscles. A large percentage of children with MDC1A are faced with respiratory as well as...

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Detalhes bibliográficos
Main Authors: Kumar, Ajay, Yamauchi, Jenny, Girgenrath, Tanya, Girgenrath, Mahasweta
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098729/
https://ncbi.nlm.nih.gov/pubmed/21441569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr126
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