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Engineering Dendritic Cells to Enhance Cancer Immunotherapy

Cancer immunotherapy aims to establish immune-mediated control of tumor growth by priming T-cell responses to target tumor-associated antigens. Three signals are required for T-cell activation: (i) presentation of cognate antigen in self MHC molecules; (ii) costimulation by membrane-bound receptor-l...

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Detalhes bibliográficos
Main Authors: Boudreau, Jeanette E, Bonehill, Aude, Thielemans, Kris, Wan, Yonghong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098642/
https://ncbi.nlm.nih.gov/pubmed/21468005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.57
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