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Chemoprevention of Murine Lung Cancer by Gefitinib in Combination with Prostacyclin Synthase Overexpression
INTRODUCTION: We hypothesized that the combination of the EGFR tyrosine kinase inhibitor (TKI) gefitinib with the powerful chemopreventive manipulation of lung specific transgenic prostacyclin synthase (PGIS) overexpression on tumorigenesis in FVB/N mice would result in augmented chemoprevention. MA...
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Main Authors: | , , , , , |
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格式: | Artigo |
語言: | Inglês |
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2010
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098617/ https://ncbi.nlm.nih.gov/pubmed/20116128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2010.01.004 |
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