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Transcription of human 5S rRNA genes is influenced by an upstream DNA sequence.

Six human 5S rRNA genes and gene variants and one pseudogene have been sequenced. The six genes/variants were transcribed in a HeLa cell extract with about equal efficiency. Three genes contain the Sp1 binding sequence GGGCGG in position -43 to -38 and three genes contain the Sp1 like sequence GGGCC...

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Udgivet i:Nucleic Acids Res
Principais autores: Nielsen, J N, Hallenberg, C, Frederiksen, S, Sørensen, P D, Lomholt, B
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1993
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8367278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.16.3631
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