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Inferring functional modules of protein families with probabilistic topic models

BACKGROUND: Genome and metagenome studies have identified thousands of protein families whose functions are poorly understood and for which techniques for functional characterization provide only partial information. For such proteins, the genome context can give further information about their func...

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Detalhes bibliográficos
Main Authors: Konietzny, Sebastian GA, Dietz, Laura, McHardy, Alice C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098182/
https://ncbi.nlm.nih.gov/pubmed/21554720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-141
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