Sites Inferred by Metabolic Background Assertion Labeling (SIMBAL): adapting the Partial Phylogenetic Profiling algorithm to scan sequences for signatures that predict protein function

BACKGROUND: Comparative genomics methods such as phylogenetic profiling can mine powerful inferences from inherently noisy biological data sets. We introduce Sites Inferred by Metabolic Background Assertion Labeling (SIMBAL), a method that applies the Partial Phylogenetic Profiling (PPP) approach lo...

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Bibliographische Detailangaben
Hauptverfasser: Selengut, Jeremy D, Rusch, Douglas B, Haft, Daniel H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Methodology Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098086/
https://ncbi.nlm.nih.gov/pubmed/20102603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-52
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