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Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering

BACKGROUND: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or sub-classes, of either individuals or genes. Performing a cluster analysis commonly involve decisions on how to; handle mis...

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Bibliografiske detaljer
Main Authors: Freyhult, Eva, Landfors, Mattias, Önskog, Jenny, Hvidsten, Torgeir R, Rydén, Patrik
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098084/
https://ncbi.nlm.nih.gov/pubmed/20937082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-503
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