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Germline competence of mouse ES and iPS cell lines: Chimera technologies and genetic background
In mice, gene targeting by homologous recombination continues to play an essential role in the understanding of functional genomics. This strategy allows precise location of the site of transgene integration and is most commonly used to ablate gene expression (“knock-out”), or to introduce mutant or...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3097913/ https://ncbi.nlm.nih.gov/pubmed/21607104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4252/wjsc.v1.i1.22 |
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