Two Naturally Occurring Terpenes, Dehydrocostuslactone and Costunolide, Decrease Intracellular GSH Content and Inhibit STAT3 Activation

The main purpose of the present study is to envisage the molecular mechanism of inhibitory action ofdehydrocostuslactone (DCE) andcostunolide (CS), two naturally occurring sesquiterpene lactones, towards the activation of signal transducer and activator of transcription 3 (STAT3). We report that, in...

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Autores principales: Butturini, Elena, Cavalieri, Elisabetta, Carcereri de Prati, Alessandra, Darra, Elena, Rigo, Antonella, Shoji, Kazuo, Murayama, Norie, Yamazaki, Hiroshi, Watanabe, Yasuo, Suzuki, Hisanori, Mariotto, Sofia
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097233/
https://ncbi.nlm.nih.gov/pubmed/21625597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020174
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