Identification of Small-Molecule Inhibitors of Yersinia pestis Type III Secretion System YscN ATPase

Yersinia pestis is a Gram negative zoonotic pathogen responsible for causing bubonic and pneumonic plague in humans. The pathogen uses a type III secretion system (T3SS) to deliver virulence factors directly from bacterium into host mammalian cells. The system contains a single ATPase, YscN, necessa...

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Autores principales: Swietnicki, Wieslaw, Carmany, Daniel, Retford, Michael, Guelta, Mark, Dorsey, Russell, Bozue, Joel, Lee, Michael S., Olson, Mark A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097197/
https://ncbi.nlm.nih.gov/pubmed/21611119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019716
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