Immortalized, premalignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA

INTRODUCTION: During selective segregation of DNA, a cell asymmetrically divides and retains its template DNA. Asymmetric division yields daughter cells whose genome reflects that of the parents, simultaneously protecting the parental cell from genetic errors that may occur during DNA replication. W...

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Main Authors: Bussard, Karen M, Boulanger, Corinne A, Kittrell, Frances S, Behbod, Fariba, Medina, Daniel, Smith, Gilbert H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096979/
https://ncbi.nlm.nih.gov/pubmed/20964820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2754
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