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Extreme loss of immunoreactive p-Akt and p-Erk1/2 during routine fixation of primary breast cancer

INTRODUCTION: Very few studies have investigated whether the time elapsed between surgical resection and tissue fixation or the difference between core-cut and excision biopsies impact on immunohistochemically measured biomarkers, including phosphorylated proteins in primary breast cancer. The aim o...

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Autori principali: Pinhel, Isabel F, MacNeill, Fiona A, Hills, Margaret J, Salter, Janine, Detre, Simone, A'Hern, Roger, Nerurkar, Ashutosh, Osin, Peter, Smith, Ian E, Dowsett, Mitch
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096968/
https://ncbi.nlm.nih.gov/pubmed/20920193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2719
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