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The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast

BACKGROUND: Surprisingly, in several multi-cellular eukaryotes optimal codon use correlates negatively with gene length. This contrasts with the expectation under selection for translational accuracy. While suggested explanations focus on variation in strength and efficiency of translational selecti...

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Detalhes bibliográficos
Autor principal: Stoletzki, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096941/
https://ncbi.nlm.nih.gov/pubmed/21481245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-93
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