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Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer

BACKGROUND: Interleukin-13 Receptor α2 (IL-13Rα2) is a tumor-associated antigen and target for cancer therapy. Since IL-13Rα2 is heterogeneously overexpressed in a variety of human cancers, it would be highly desirable to uniformly upregulate IL-13Rα2 expression in tumors for optimal targeting. METH...

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書誌詳細
主要な著者: Fujisawa, Toshio, Joshi, Bharat H, Puri, Raj K
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096924/
https://ncbi.nlm.nih.gov/pubmed/21477288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-37
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