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Perturbation of the Glutamate–Glutamine System in Alcohol Dependence and Remission

As acute ethanol exposure inhibits N-methyl--aspartate glutamate (Glu) receptors, sudden withdrawal from chronic alcohol use may lead to an increased activation of these receptors with excitotoxic effects. In the longer term, brain levels of Glu and its metabolites, such as glutamine (Gln), are like...

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Detalhes bibliográficos
Main Authors: Thoma, Robert, Mullins, Paul, Ruhl, David, Monnig, Mollie, Yeo, Ronald A, Caprihan, Arvind, Bogenschutz, Michael, Lysne, Per, Tonigan, Scott, Kalyanam, Ravi, Gasparovic, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096805/
https://ncbi.nlm.nih.gov/pubmed/21389979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.20
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