Perturbation of the Glutamate–Glutamine System in Alcohol Dependence and Remission

As acute ethanol exposure inhibits N-methyl--aspartate glutamate (Glu) receptors, sudden withdrawal from chronic alcohol use may lead to an increased activation of these receptors with excitotoxic effects. In the longer term, brain levels of Glu and its metabolites, such as glutamine (Gln), are like...

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Hlavní autoři: Thoma, Robert, Mullins, Paul, Ruhl, David, Monnig, Mollie, Yeo, Ronald A, Caprihan, Arvind, Bogenschutz, Michael, Lysne, Per, Tonigan, Scott, Kalyanam, Ravi, Gasparovic, Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096805/
https://ncbi.nlm.nih.gov/pubmed/21389979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.20
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