Clostridium difficile Transcriptome Analysis Using Pig Ligated Loop Model Reveals Modulation of Pathways Not Modulated In Vitro

A pig ligated loop model was used to analyze the in vivo transcriptome response of Clostridium difficile. Bacterial RNA from the loops was retrieved at different times and was used for microarray analysis. Several virulence-associated genes and genes involved in sporulation cascade were differential...

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Bibliographic Details
Main Authors: Scaria, Joy, Janvilisri, Tavan, Fubini, Susan, Gleed, Robin D., McDonough, Sean P., Chang, Yung-Fu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096783/
https://ncbi.nlm.nih.gov/pubmed/21592991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir112
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