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Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4(+) T cells to T regulatory cells

Pulmonary metastasis of breast cancer requires recruitment and expansion of T regulatory cells (Tregs) that promote escape from host protective immune cells. However, it remains unclear precisely how tumors recruit Tregs to support metastatic growth. Here we report the mechanistic involvement of a u...

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Autori principali: Olkhanud, Purevdorj B., Damdinsuren, Bazarragchaa, Bodogai, Monica, Gress, Ronald E., Sen, Ranjan, Wejksza, Katarzyna, Malchinkhuu, Enkhzol, Wersto, Robert P., Biragyn, Arya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096701/
https://ncbi.nlm.nih.gov/pubmed/21444674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4316
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