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A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression

Aberrant activation of Wnt/β-catenin signaling, resulting in the expression of Wnt regulated oncogenes, is recognized as a critical factor in the etiology of colorectal cancer. Occupancy of β-catenin at promoters of Wnt target genes drives transcription, but the mechanism of β-catenin action remains...

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Detalhes bibliográficos
Main Authors: Ou, Chen-Yin, LaBonte, Melissa J., Manegold, Philipp C., So, Alex Yick-Lun, Ianculescu, Irina, Gerke, Daniel S., Yamamoto, Keith R., Ladner, Robert D., Kahn, Michael, Kim, Jeong Hoon, Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096696/
https://ncbi.nlm.nih.gov/pubmed/21478268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0223
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