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Oxygen levels that optimize TSC culture are identified by maximizing growth rates and minimizing stress

Accumulating data suggest that 20% O2 causes human and mouse placental trophoblast stem cell (TSC) differentiation and suppresses proliferation. We tested the hypotheses that phosphorylated stress-activated protein kinase (pSAPK) levels report the optimal O2 level for TSC culture, and that pSAPK res...

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Detalhes bibliográficos
Main Authors: Zhou, S, Xie, Y, Puscheck, EE, Rappolee, DA
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096684/
https://ncbi.nlm.nih.gov/pubmed/21511332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2011.03.013
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