Lovastatin Inhibits the Thrombin-Induced Loss of Barrier Integrity in Bovine Corneal Endothelium

PURPOSE: Increased actomyosin contraction of the dense band of actin cytoskeleton at the apical junctional complex (perijunctional actomyosin ring, PAMR) breaks down the barrier integrity of corneal endothelium. This study has investigated the efficacy of statins, which inhibit activation of RhoA, i...

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Bibliografske podrobnosti
Main Authors: Shivanna, Mahesh, Jalimarada, Supriya S., Srinivas, Sangly P.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. publishers 2010
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096541/
https://ncbi.nlm.nih.gov/pubmed/20148651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2009.0025
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