In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide.

Oligonucleotides provide novel reagents for inhibition of gene expression because of their high affinity binding to specific nucleotide sequences. We describe a 38 base, single-stranded DNA that forms a triple helix or 'triplex' on progesterone response elements of a target gene. This trip...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ing, N H, Beekman, J M, Kessler, D J, Murphy, M, Jayaraman, K, Zendegui, J G, Hogan, M E, O'Malley, B W, Tsai, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC309654/
https://ncbi.nlm.nih.gov/pubmed/8332487
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados