Connexin43 Hemichannels Contribute to Cadmium-Induced Oxidative Stress and Cell Injury

We investigated the potential involvement of connexin hemichannels in cadmium ions (Cd(2+))-elicited cell injury. Transfection of LLC-PK1 cells with a wild-type connexin43 (Cx43) sensitized them to Cd(2+)-elicited cell injury. The cell susceptibility to Cd(2+) was increased by depletion of glutathio...

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Autors principals: Fang, Xin, Huang, Tao, Zhu, Ying, Yan, Qiaojing, Chi, Yuan, Jiang, Jean X., Wang, Peiyu, Matsue, Hiroyuki, Kitamura, Masanori, Yao, Jian
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2011
Matèries:
Original Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096519/
https://ncbi.nlm.nih.gov/pubmed/21235398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3150
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