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SOD1 Transcriptional and Posttranscriptional Regulation and Its Potential Implications in ALS

Copper-zinc superoxide dismutase (SOD1) is a detoxifying enzyme localized in the cytosol, nucleus, peroxisomes, and mitochondria. The discovery that mutations in SOD1 gene cause a subset of familial amyotrophic lateral sclerosis (FALS) has attracted great attention, and studies to date have been mai...

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Detalhes bibliográficos
Main Authors: Milani, Pamela, Gagliardi, Stella, Cova, Emanuela, Cereda, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096450/
https://ncbi.nlm.nih.gov/pubmed/21603028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/458427
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