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Genomic Imprinting Controls Matrix Attachment Regions in the Igf2 Gene

Genomic imprinting at the Igf2/H19 locus originates from allele-specific DNA methylation, which modifies the affinity of some proteins for their target sequences. Here, we show that AT-rich DNA sequences located in the vicinity of previously characterized differentially methylated regions (DMRs) of...

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Bibliografiske detaljer
Main Authors: Weber, Michaël, Hagège, Hélène, Murrell, Adele, Brunel, Claude, Reik, Wolf, Cathala, Guy, Forné, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC309645/
https://ncbi.nlm.nih.gov/pubmed/14645508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.24.8953-8959.2003
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