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Use of Allopurinol to Optimize Thiopurine Immunomodulator Efficacy in Inflammatory Bowel Disease

The thiopurine immunomodulators azathioprine and 6-mercaptopurine are integral to the management of inflammatory bowel disease (IBD), particularly as corticosteroid-sparing and maintenance agents; however, up to 50% of patients do not adequately respond to these agents. Advances in pharmacogenomics...

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Autor principal: Sparrow, Miles P.
Format: Artigo
Idioma:Inglês
Publicat: Millennium Medical Publishing 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096137/
https://ncbi.nlm.nih.gov/pubmed/21960930
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