Self-stabilized antisense oligodeoxynucleotide phosphorothioates: properties and anti-HIV activity.
A new class of oligodeoxyribonucleotides has been designed, referred to here as 'self-stabilized' oligonucleotides. These oligonucleotides have hairpin loop structures at their 3' ends, and show increased resistance to degradation by snake venom phosphodiesterase, DNA polymerase I and fetal bovine s...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1993
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.11.2729 |
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