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Self-stabilized antisense oligodeoxynucleotide phosphorothioates: properties and anti-HIV activity.

A new class of oligodeoxyribonucleotides has been designed, referred to here as 'self-stabilized' oligonucleotides. These oligonucleotides have hairpin loop structures at their 3' ends, and show increased resistance to degradation by snake venom phosphodiesterase, DNA polymerase I and fetal bovine s...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Tang, J Y, Temsamani, J, Agrawal, S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1993
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309610/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8392706/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.11.2729
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