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SID-1 is a dsRNA-selective dsRNA-gated channel
Systemic RNAi in Caenorhabditis elegans requires the widely conserved transmembrane protein SID-1 to transport RNAi silencing signals between cells. When expressed in Drosophila S2 cells, C. elegans SID-1 enables passive dsRNA uptake from the culture medium, suggesting that SID-1 functions as a chan...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096038/ https://ncbi.nlm.nih.gov/pubmed/21474576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2596511 |
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