A Role for Matrix Metalloproteinase 9 in IFNγ-Mediated Injury in Developing Lungs: Relevance to Bronchopulmonary Dysplasia

We noted a marked increase in IFNγ mRNA in newborn (NB) murine lungs after exposure to hyperoxia. We sought to evaluate the role of IFNγ in lung injury in newborns. Using a unique triple-transgenic (TTG), IFNγ-overexpressing, lung-targeted, externally regulatable NB murine model, we describe a lung...

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Hlavní autoři: Harijith, Anantha, Choo-Wing, Rayman, Cataltepe, Sule, Yasumatsu, Ryuji, Aghai, Zubair H., Janér, Joakim, Andersson, Sture, Homer, Robert J., Bhandari, Vineet
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095982/
https://ncbi.nlm.nih.gov/pubmed/21216975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0058OC
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