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Increased Expression of Angiopoietins and Tie2 in the Lungs of Chronic Asthmatic Mice

Angiopoietin (Ang)1 and Ang2 are ligands for Tie2 tyrosine kinase receptor (Tie2). Elevated levels of Ang1 and Ang2 in induced sputum of patients with asthma have been reported, with a positive correlation of Ang2 levels with the severity of airway occlusion. Although studies have shown Tie2-mediate...

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Main Authors: Makinde, Toluwalope O., Agrawal, Devendra K.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095938/
https://ncbi.nlm.nih.gov/pubmed/20463289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0330OC
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