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Regulatory T Cells Contribute to Allergen Tolerance Induced by Daily Airway Immunostimulant Exposures

Endotoxin and other immunostimulants ubiquitous in ambient air are potent mucosal adjuvants, yet only a minority of individuals develop aeroallergen hypersensitivities, whereas the majority develop tolerance. These investigations were performed to reconcile this paradox. During initial experiments,...

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Detalhes bibliográficos
Main Authors: Lee, Steve M., Batzer, Glenda, Ng, Nicholas, Lam, Diane, Pattar, Sundeep S., Patel, Neal D., Horner, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095935/
https://ncbi.nlm.nih.gov/pubmed/20448052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0001OC
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