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The Primary DNA-Binding Subsite of the Rat Pol β Energetics of Interactions of the 8-kDa Domain of the Enzyme With the ssDNA

Interactions of the 8-kDa domain of the rat pol β and the intact enzyme with the ssDNA have been studied, using the quantitative fluorescence titration technique. The 8-kDa domain induces large topological changes in the bound DNA structure and engages much larger fragments of the DNA than when embe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jezewska, Maria J., Szymanski, Michal R., Bujalowski, Wlodzimierz
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095670/
https://ncbi.nlm.nih.gov/pubmed/21382659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2011.01.006
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