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Effects of 7-keto Dehydroepiandrosterone on Voluntary Ethanol Intake in Male Rats

Administration of dehydroepiandrosterone (DHEA), a neurosteroid that can negatively modulate the GABA(A) receptor, has been shown to decrease voluntary intake of ethanol in rats. In vivo, DHEA can be metabolized to a variety of metabolites, including 7-keto DHEA, a metabolite without the prohormonal...

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Bibliographic Details
Main Authors: Worrel, Mary E., Gurkovskaya, Olga V., Leonard, Stuart T., Lewis, Peter B., Winsauer, Peter J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095668/
https://ncbi.nlm.nih.gov/pubmed/21051179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2010.08.020
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