TRESK channel contribution to nociceptive sensory neurons excitability: modulation by nerve injury

BACKGROUND: Neuronal hyperexcitability is a crucial phenomenon underlying spontaneous and evoked pain. In invertebrate nociceptors, the S-type leak K(+ )channel (analogous to TREK-1 in mammals) plays a critical role of in determining neuronal excitability following nerve injury. Few data are availab...

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Autori principali: Tulleuda, Astrid, Cokic, Barbara, Callejo, Gerard, Saiani, Barbara, Serra, Jordi, Gasull, Xavier
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095542/
https://ncbi.nlm.nih.gov/pubmed/21527011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-30
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