Anti-IL-6 Receptor Antibody Causes Less Promotion of Tuberculosis Infection than Anti-TNF-α Antibody in Mice

Objective. Our aim was to investigate the effects of IL-6 blockade on the progression of Mycobacterium tuberculosis (TB) and compare them with those of TNF-α blockade in mice. Methods. Mice were intravenously infected with TB and injected with antibodies. Survival was monitored and histological and...

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Hauptverfasser: Okada, Masaji, Kita, Yoko, Kanamaru, Noriko, Hashimoto, Satomi, Uchiyama, Yasushi, Mihara, Masahiko, Inoue, Yoshikazu, Ohsugi, Yoshiyuki, Kishimoto, Tadamitsu, Sakatani, Mitsunori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095415/
https://ncbi.nlm.nih.gov/pubmed/21603208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/404929
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