IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge

Staphylococcus aureus is the most frequent cause of bacteremia and hospital-acquired infection, however a vaccine that prevents staphylococcal disease is currently not available. Two sortase-anchored surface proteins, IsdA and IsdB, have been identified as subunit vaccines that, following active imm...

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Bibliografiske detaljer
Main Authors: Kim, Hwan Keun, DeDent, Andrea, Cheng, Alice G., McAdow, Molly, Bagnoli, Fabio, Missiakas, Dominique M., Schneewind, Olaf
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095377/
https://ncbi.nlm.nih.gov/pubmed/20226248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.02.097
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