AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV-1157ipd3N4

A Chinese rhesus macaque infected with the pathogenic CCR5-tropic clade C simian-human immunodeficiency virus, SHIV-1157ipd3N4, had persistent viremia, depletion of CD4(+) T cells to <200 cells/μl, opportunistic infections, coagulopathy and gradual development of bilateral blindness. MRI revealed...

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Main Authors: Garcia, Ana Patricia, Siddappa, Nagadenahalli B., Li, Qingsheng, Haase, Ashley T., Paul, Katherine, Stroud, Fawn, Zhang, Xiaodong, Fountain, Jack A., Villinger, Francois, Novembre, Francis J., Else, James G, Secor, W. Evan, Ruprecht, Ruth M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095218/
https://ncbi.nlm.nih.gov/pubmed/20412378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0684.2010.00416.x
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