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A Di-Leucine Sequence and a Cluster of Acidic Amino Acids Are Required for Dynamic Retention in the Endosomal Recycling Compartment of Fibroblasts

Insulin-regulated aminopeptidase (IRAP), a transmembrane aminopeptidase, is dynamically retained within the endosomal compartment of fibroblasts. The characteristics of this dynamic retention are rapid internalization from the plasma membrane and slow recycling back to the cell surface. These specia...

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Detalhes bibliográficos
Main Authors: Johnson, Amy O., Lampson, Michael A., McGraw, Timothy E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30949/
https://ncbi.nlm.nih.gov/pubmed/11179421
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