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A Di-Leucine Sequence and a Cluster of Acidic Amino Acids Are Required for Dynamic Retention in the Endosomal Recycling Compartment of Fibroblasts

Insulin-regulated aminopeptidase (IRAP), a transmembrane aminopeptidase, is dynamically retained within the endosomal compartment of fibroblasts. The characteristics of this dynamic retention are rapid internalization from the plasma membrane and slow recycling back to the cell surface. These specia...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Amy O., Lampson, Michael A., McGraw, Timothy E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC30949/
https://ncbi.nlm.nih.gov/pubmed/11179421
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