γH2AX and cancer

Histone H2AX phosphorylation on a serine four residues from the carboxyl terminus (producing γH2AX) is a sensitive marker for DNA double-strand breaks (DSBs). DSBs may lead to cancer but, paradoxically, are also used to kill cancer cells. Using γH2AX detection to determine the extent of DSB inductio...

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Autores principales: Bonner, William M., Redon, Christophe E., Dickey, Jennifer S., Nakamura, Asako J., Sedelnikova, Olga A., Solier, Stéphanie, Pommier, Yves
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094856/
https://ncbi.nlm.nih.gov/pubmed/19005492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2523
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