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Endothelial Nitric Oxide Synthase Gene Variants and Primary Open-Angle Glaucoma: Interactions with Sex and Postmenopausal Hormone Use

PURPOSE. To evaluate the association between the nitric oxide synthase gene (NOS3) variants and primary open-angle glaucoma (POAG). METHODS. Two functional single-nucleotide polymorphisms (SNPs) (T−786C: rs2070744; Glu298Asp: rs1799983) and three tagging SNPs (rs7830, rs3918188, and rs1800779) were...

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Detalhes bibliográficos
Main Authors: Kang, Jae Hee, Wiggs, Janey L., Rosner, Bernard A., Hankinson, Susan E., Abdrabou, Wael, Fan, Bao Jian, Haines, Jonathan, Pasquale, Louis R.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094851/
https://ncbi.nlm.nih.gov/pubmed/19815736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4266
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