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Phosphorylation of a Conserved Integrin α3 QPSXXE Motif Regulates Signaling, Motility, and Cytoskeletal Engagement

Integrin α3A cytoplasmic tail phosphorylation was mapped to amino acid S1042, as determined by mass spectrometry, and confirmed by mutagenesis. This residue occurs within a “QPSXXE” motif conserved in multiple α chains (α3A, α6A, α7A), from multiple species. Phosphorylation of α3A and α6A did not ap...

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Autors principals: Zhang, Xin A., Bontrager, Alexa L., Stipp, Christopher S., Kraeft, Stine-Kathrein, Bazzoni, Gianfranco, Chen, Lan Bo, Hemler, Martin E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC30948/
https://ncbi.nlm.nih.gov/pubmed/11179420
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