A new method for specific cleavage of megabase-size chromosomal DNA by lambda-terminase.
The development of methods for cleavage of DNA at specific site(s) that are widely spaced would facilitate physical mapping of large genomes. Several methods for rare and specific cleavage of chromosomal DNAs require a nearly complete methylation of a given type of restriction site except the one th...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1993
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8502555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.9.2143 |
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