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Lack of primary cilia primes shear-induced Endothelial-to-Mesenchymal Transition

RATIONALE: Primary cilia are cellular protrusions which serve as mechanosensors for fluid flow. In endothelial cells (EC) they function in transducing local blood flow information into functional responses, like nitric oxide production and initiation of gene expression. Cilia are present on EC in ar...

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Detalhes bibliográficos
Main Authors: Egorova, Anastasia D., Khedoe, Padmini P.S.J., Goumans, Marie-José T.H., Yoder, Bradley K., Nauli, Surya M., Dijke, Peter ten, Poelmann, Robert E., Hierck, Beerend P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094764/
https://ncbi.nlm.nih.gov/pubmed/21393577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.231860
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