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Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration

Telomeres comprise long tracts of double-stranded TTAGGG repeats that extend for 9–15 kb in humans. Telomere length is maintained by telomerase, a specialized ribonucleoprotein that prevents the natural ends of linear chromosomes from undergoing inappropriate repair, which could otherwise lead to de...

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Detalhes bibliográficos
Main Authors: Madonna, Rosalinda, De Caterina, Raffaele, Willerson, James T., Geng, Yong-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094547/
https://ncbi.nlm.nih.gov/pubmed/21148539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehq450
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