Purification and Characterization of Enterovirus 71 Viral Particles Produced from Vero Cells Grown in a Serum-Free Microcarrier Bioreactor System

BACKGROUND: Enterovirus 71 (EV71) infections manifest most commonly as a childhood exanthema known as hand-foot-and-mouth disease (HFMD) and can cause neurological disease during acute infection. PRINCIPAL FINDING: In this study, we describe the production, purification and characterization of EV71...

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Detalhes bibliográficos
Main Authors: Liu, Chia-Chyi, Guo, Meng-Shin, Lin, Fion Hsiao-Yu, Hsiao, Kuang-Nan, Chang, Kate Hsuen-Wen, Chou, Ai-Hsiang, Wang, Yu-Chao, Chen, Yu-Ching, Yang, Chung-Shi, Chong, Pele Choi-Sing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094384/
https://ncbi.nlm.nih.gov/pubmed/21603631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020005
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