Occurrence of multipolar mitoses and association with Aurora-A/-B kinases and p53 mutations in aneuploid esophageal carcinoma cells

BACKGROUND: Aurora kinases and loss of p53 function are implicated in the carcinogenesis of aneuploid esophageal cancers. Their association with occurrence of multipolar mitoses in the two main histotypes of aneuploid esophageal squamous cell carcinoma (ESCC) and Barrett's adenocarcinoma (BAC)...

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Autores principales: Fichter, Christiane D, Herz, Corinna, Münch, Claudia, Opitz, Oliver G, Werner, Martin, Lassmann, Silke
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094318/
https://ncbi.nlm.nih.gov/pubmed/21470402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-12-13
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